|Kayser Söze shoots left handed in Verbal Kint's story|
|Left-handed "Kayser" shoots Keaton on the ship|
Kint himself seems to be right handed, though this may be a result of his apparent disability. He is played as having cerebral palsy affecting one leg and one arm. He holds his Uzi right handed in one scene.
In case you haven't seen the movie, I'll just leave it at that. Except to comment that writer Christopher McQuarrie and director Bryan Singer seem to have thought of everything.
Kevin Spacey, who played Verbal Kint, appears to be right handed.